A much abused substance may have a negative impact on bone growth:
In Medicine, paracetamol is used to soothe every kind of pain, from simple molar pain to pain produced by bone fractures. This medicine is one of the most used nowadays. However, [researchers] showed that taking paracetamol slows down bone growth, as has been proved by ‘in vitro’ studies.
This research is very theoretic ie it has been carried out in a petri dish and the assumption is that the same process takes place in the body. It may be a stretch. However given the role of bones in the regulation of insulin, this may be a factor to consider for those trying to improve their insulin sensitivity.